GENEAe018-A

Not yet reviewed by Australian Stem Cell Registry

GENEA090

Details

Tissue & Disease as reported

Disease as reported (Donor)
huntington disease

Genetic Information

No genetic information available for this cell line

Associated Publications

Journal Year Article
Stem cell research 2016 Derivation of Huntington Disease affected Genea090 human embryonic stem cell line
Journal of proteome research 2014 Proteomics of Huntington's disease-affected human embryonic stem cells reveals an evolving pathology involving mitochondrial dysfunction and metabolic disturbances

Line Custodianship

Cell Line Maintainer

Biocells

Affiliated Institutions
  • Biocells, San Diego, United States
View all cell lines from this group

Cell Line Producer

Genea

Affiliated Institutions
  • Genea, San Diego, United States

Source

Donor Derived

Age: Unknown

Biological Sex: Female

Disease: MONDO:0007739
Label: Huntington disease
Definition: Huntington disease (HD) is a rare neurodegenerative disorder of the central nervous system characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia.

Derivation Details

Induced Pluripotent Cell Derivation Details

Source Cell Type: N/A

Source Cell Origin: N/A

Derivation Year:

Ethics

Ethics Number: Licence 309710

Institution Human Research Ethics Council: NHMRC

Approval Date: To be verified

Modifications

No genomic modifications available for this line.

Quality Assurance

Genomic Characterisation

Passage Number: 9

Karyotype: 46 XX, no abnormalities detected

Karyotype Method: Other

STR analysis Results:

Performed but not available.

Microbiology and Virology Screening

No available data for this cell line.

Characterisation of Undifferentiated Cells

Marker Method
NANOG Immunostaining
SSEA-4 Immunostaining
TRA 1-60 Immunostaining
POU5F1 (OCT-4) Immunostaining

Scorecard Results

Undifferentiated Cells

No available data for this cell line.

Pluripotency

No available data for this cell line.

Pluripotency Characterisation

Mesoderm

None

Assessed by: Unavailable

Markers:

Ectoderm

None

Assessed by: Unavailable

Markers:

Growth Characteristics

Culture Medium and Growth Conditions

CO2 concentration: Unavailable

O2 concentration: Unavailable

Medium Items:

Passage Method: Not specified